Growth and Trends in the Preparative and Process Chromatography Market (2024-2034)

The global market for preparative and process chromatography is valued at USD 11.36 billion in 2024, with expectations to reach USD 12.39 billion in 2025. By 2034, it is projected to grow to approximately USD 27.16 billion, reflecting a compound annual growth rate (CAGR) of 9.11% from 2025 to 2034. This growth is driven by rising demand for biopharmaceutical products such as insulin, innovations in chromatography techniques, and increased research and development efforts.

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Market Overview

Chromatography is a laboratory technique used to separate and purify components from a mixture through various methods. Analytical chromatography is primarily used for research analysis, while preparative chromatography focuses on isolating and purifying sufficient quantities of a specific component. Process chromatography separates mixture components by leveraging differences in their mobility through a column.

Preparative and process chromatography are essential techniques in various industries. They are crucial for the production of pharmaceuticals, biomolecules, food ingredients, and chemicals. The growing pharmaceutical and biotechnology research sectors, along with the need for pure compounds in large-scale processing, are key factors propelling the market forward. Stringent regulations and increasing technological investments are also fueling market expansion.

Key Trends in the Market

In September 2024, Gilson introduced the VERITY Preparative LC system, a purification platform designed to support contract research organizations (CROs) and biotech R&D groups in drug discovery, such as peptide and oligonucleotide production.

Tecan launched the Resolvex Prep in October 2023, a benchtop automation solution aimed at improving the efficiency and precision of chromatography sample preparation.

Shimadzu Corporation, a major player in the chromatography industry, reported strong financial performance in 2024, with net sales of 116,938 million yen in Q1 and a 17.3% operating profit. The company remains a leader in providing advanced analytical instruments, including chromatography systems and mass spectrometry solutions.

Segment Insights in the Preparative and Process Chromatography Market

Process Chromatography Segment Leads the Market
In 2024, the process chromatography segment held the largest share of the preparative and process chromatography market. This technique is widely used in the development and production of biopharmaceuticals and biologicals for diagnostic purposes. The increasing demand for biological products as therapeutic treatments, along with the rapid growth of the biotech industry, is fueling the expansion of this segment. Additionally, the need for large-scale production of biologicals further boosts the demand for process chromatography.

Preparative Chromatography Segment: Fastest Growth
The preparative chromatography segment is expected to experience the fastest growth in the market during the forecast period. This growth is driven by the increasing need for purifying pharmaceutical products, the development of more advanced purification techniques, and the rising demand for efficient and cost-effective processes in pharmaceutical and biotechnology industries.

Liquid Chromatography Segment Leads in 2024
By type, liquid chromatography was the dominant technique in the global market in 2024. This method separates molecules using a liquid mobile phase and a solid stationary phase. Liquid chromatography is versatile and can be applied to various samples, as long as the product can dissolve in the liquid phase. Automation of liquid chromatography equipment has made it more accessible and user-friendly, contributing to its widespread use in research and industry.

Hydrophobic Interaction Chromatography: Fastest Growth in Type
The hydrophobic interaction chromatography (HIC) segment is expected to grow at the highest rate during the forecast period. HIC is used to separate and purify proteins and biomolecules based on their interaction with hydrophobic ligands. This technique is essential for purifying proteins needed in biotechnology, pharmaceuticals, and medical diagnostics, driving its market growth.

Pharmaceutical Sector Holds the Largest Market Share
In terms of end-use, the pharmaceutical sector accounted for the largest share of the market in 2024. This growth is driven by the increasing demand for new drug discoveries, ongoing research and development activities, and the expanding global pharmaceutical industry.

Biotechnology Sector: Significant Growth Ahead
The biotechnology segment is expected to see significant growth over the forecast period. This growth is fueled by the expanding biotech sector, the rising demand for biologic therapeutics like vaccines and monoclonal antibodies, and increasing investments in biotechnology research and development.

Our Table of Content (TOC) covers key healthcare market segments, materials, technologies and trends—helping you navigate market shifts and make informed decisions: https://www.towardshealthcare.com/table-of-content/preparative-and-process-chromatography-market-size

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