Overview of the microRNA Market

The global microRNA market was valued at $1.61 billion in 2023 and is projected to reach $6.11 billion by 2034, growing at a compound annual growth rate (CAGR) of 12.89% from 2024 to 2034. The increasing prevalence of chronic conditions, along with advancements in biotechnology, are key factors driving the market’s growth.

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Market Insights

• Regional Analysis:
  • North America led the market in 2023 with a 41.6% share.
  • The Asia Pacific region is expected to experience the fastest growth during the forecast period.
• Products & Services:
  • The service segment accounted for the largest market share in 2023.
• Application Areas:
  • The cancer segment dominated the market in 2023.
  • The infectious diseases segment is projected to grow at the fastest rate during the forecast period.
• End-Use Segments:
  • Biotechnology and pharmaceutical companies were the largest end-users of microRNA technologies in 2023.

The Role of microRNA in Diagnostics and Therapeutics

MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression. In the biotechnology and life sciences industries, they are critical for developing diagnostic tools and therapies. miRNAs play a vital role in controlling gene expression involved in numerous illnesses, including cancer and infectious diseases. As biomarkers, microRNAs help identify the diagnostic, prognostic, and predictive values for patient management and are pivotal in the detection of diseases in tissues and bodily fluids.

The Impact of AI on the microRNA Market

Artificial Intelligence (AI) and machine learning are revolutionizing the microRNA market by improving the discovery and development of miRNA-based therapies. Machine learning techniques help identify new miRNA biomarkers and build high-performance classification models for disease detection, such as cancer. For instance, in July 2023, researchers developed a multiclass cancer detection tool using AI and microRNA, enhancing non-invasive diagnostic methods.

Key Players in the microRNA Market

Leading companies in the microRNA market include:

• Thermo Fisher Scientific, Inc.
• DiamiR Biosciences
• New England Biolabs
• NanoString Technologies, Inc.
• Sanofi
• miRecule
• Alnylam
• BioGenex
• Merck KGaA
• LGC Limited
• Takara Bio, Inc.
• Horizon Discovery Group plc.
• QIAGEN
• GeneCopoeia, Inc.

Recent Developments by Major Companies

• DiamiR Biosciences (New Jersey, U.S.): In July 2024, DiamiR Biosciences prepared to launch its microRNA-based CogniMir blood test for Alzheimer’s risk assessment, following clinical trials. The test measures 24 microRNA targets in plasma using PCR technology.
• MiRecule (Gaithersburg, U.S.): In July 2024, MiRecule partnered with Sanofi to develop a therapy for facioscapulohumeral muscular dystrophy (FSHD) and is raising capital for further development.

Growing Number of Clinical Trials in the microRNA Market

Research into miRNAs as therapeutic targets has led to numerous clinical trials worldwide. A search of the Clinical Trials Database in January 2023 revealed 1,213 studies related to microRNA:

• 414 completed studies
• 91 ongoing studies
• 368 studies in recruitment or pre-recruitment phases

These clinical trials aim to explore miRNA’s potential in drug development, diagnosis, and screening across various human disorders.

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