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RNA-Based Therapeutic Market Key Players and Industry Insights

RNA-Based Therapeutic Market Growth and Trends

The global RNA-based therapeutic market was valued at $6.83 billion in 2023 and is expected to reach $40.81 billion by 2034, growing at a CAGR of 17.64%. This growth is driven by the use of RNA in vaccines and treatments for infectious diseases and cancer, with synthetic RNA produced through in vitro transcription using DNA plasmids.

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Market Overview

The RNA-based therapeutic market is experiencing rapid growth due to the effectiveness of in vitro transcribed (IVT) mRNA, which enters the cytoplasm and can be used for therapeutic protein replacement or immunization without making genomic changes or posing genetic risks like DNA-based therapies. RNA-based treatments can target a broader range of diseases, making them highly attractive for therapeutic development. Initially, RNA-based therapies were used to treat diseases like cancer, neurological disorders, and infectious diseases with positive results.

Recent advances in RNA technology have led to the approval of several RNA therapies, including eight antisense oligonucleotides (ASOs), three small interfering RNAs (siRNAs), and two mRNA vaccines for COVID-19 under Emergency Use Authorization. Other RNA-based drugs are currently undergoing preclinical and clinical trials. Newer, more advanced RNA therapies are also being developed. RNA therapeutics refer to the use of RNA molecules to alter biological processes in the body to treat diseases. With established nucleic acid chemistry and delivery methods, developing RNA-based drugs targeting new diseases can be done quickly, driving strong growth in the market.

Top Companies in the RNA-Based Therapeutic Market

  1. ISIS Pharmaceuticals
    Now known as Ionis Pharmaceuticals, this company is a leader in the development of antisense oligonucleotides (ASOs) for treating a variety of diseases, including genetic disorders and cancers.
  2. Quark Pharmaceuticals
    Quark Pharmaceuticals focuses on RNA-based therapeutics, particularly small interfering RNA (siRNA) drugs aimed at treating eye diseases, kidney diseases, and cancer.
  3. Alnylam Pharmaceuticals
    Alnylam is a pioneering company in the field of RNA interference (RNAi) therapies. Their innovative treatments are targeting genetic diseases, with a special focus on rare, hereditary conditions.
  4. Dicerna Pharmaceuticals
    Dicerna specializes in RNA interference (RNAi) technology to develop therapies for rare genetic diseases, liver diseases, and cancers.
  5. Tekmira Pharmaceuticals Corp.
    Tekmira is focused on advancing RNA-based drug delivery platforms, particularly in the development of RNA therapeutics for infectious diseases and cancer.
  6. Benitec Biopharma Limited
    Benitec is known for its work in developing gene-silencing therapies using RNA interference (RNAi) technology. Their therapies target diseases such as cancer, hepatitis, and genetic disorders.
  7. Genzyme Corporation
    Acquired by Sanofi, Genzyme is a leader in biotechnology, developing RNA-based treatments for genetic diseases and other chronic conditions, including rare metabolic disorders.
  8. Silence Therapeutics PLC
    Silence Therapeutics specializes in developing RNA interference therapies for a range of diseases, including cancer, cardiovascular diseases, and rare genetic disorders.
  9. Cenix BioScience GmbH
    Cenix is focused on RNA-based research and therapeutic development, utilizing RNA interference (RNAi) to target diseases like cancer, viral infections, and metabolic disorders.

Our Table of Content (TOC) covers key healthcare market segments, materials, technologies and trends—helping you navigate market shifts and make informed decisions: https://www.towardshealthcare.com/table-of-content/rna-based-therapeutic-market-sizing

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Elena Morales

Elena Morales is a healthcare industry expert working at Healthcare Web Wire Consulting Firm, a subsidiary of Towards Healthcare. With her excellent knowledge of the field, Elena helps clients optimize their operations and navigate healthcare regulations. She's dedicated to staying updated on industry trends to make a positive impact on patient care. Elena is known for her professionalism and commitment to excellence, making her a valuable asset to any team.

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